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• 1921-1974
• 1975-1999
• 2000-2007
• 2008-present

Note: All products in this table below are sold by Otsuka Pharmaceutical Factory and other Otsuka Group companies. Generally, product names are those currently used. Product photos are generally those at the time of launch.

2008	ARTCEREB irrigation and perfusion solution for cerebrospinal surgery launched
	Otsuka Holdings Co., Ltd. established
	Urepearl Plus Lotion 10 launched—a medicine for the treatment of dry skin with improved formulation, effect and use sensation
2009	Innerpower, beverage (jelly), launched
	Oral rehydration solution OS-1 Powder launched—a powder type that is convenient for carrying around
	ELNEOPA No. 1/No. 2 Injection launched—a TPN formulation containing glucose, electrolytes, amino acids, multiple vitamins, and trace elements
	HINE Jelly Aqua launched—a concentrated liquid diet with added water
2010	BICANATE Injection launched—a bicarbonated Ringer’s solution
	Otsuka Holdings Co., Ltd. listed on the First Section of the Tokyo Stock Exchange
2011	Sodium Phosphate Corrective Injection 0.5 mmol/mL launched—a corrective electrolyte solution
	RACOL-NF Liquid for Enteral Use, a low residual diet preparation (for feeding tube and oral administration), and Twinline-NF Liquid for Enteral Use, an elemental diet preparation, launched
	Diatranz Otsuka Limited established in New Zealand
2012	Oral rehydration solution OS-1 Powder approved as food for persons with medical conditions (individually evaluated type) categorized as food for special dietary use by the Consumer Affairs Agency
2013	Voluven 6% Solution for Infusion launched - a plasma substitute
	Capital participation in Claris Otsuka Private Limited (currently Otsuka Pharmaceutical India Private Limited)
2014	ENGELEAD Apple Jelly and ENGELEAD Grape Jelly approved as a food for special dietary use, food for persons who have difficulty swallowing (approval standardⅠ) by the Consumer Affairs Agency
	HINE E-Gel launched—a concentrated liquid diet that changes state from liquid to gel form in reaction with stomach acids
	Povidone-iodine Solution 10% Antiseptic Applicator Otsuka 10 mL/25 mL launched—an external-use antiseptic
	RACOL-NF SemiSolid for Enteral Use launched—an enteral nutrient solution
	Shinichi Ogasawara appointed President
	Acquired a local pharmaceutical company in Egypt as a subsidiary (currently Otsuka Al-Obour Pharmaceutical Egypt S.A.E.)
	PROCESS LEAD launched—a chew and swallow managing food that takes into account physical properties after chewing
2015	Lilium Otsuka Co., Ltd. established
	Olanedine Antiseptic Solution 1.5% and Olanedine Solution 1.5% Antiseptic Applicator launched—an external-use antiseptic
2016	Lilium α-200 launched - an ultrasound bladder imaging device
2017	ELNEOPA-NF No. 1/No. 2 Injection launched—a TPN formulation containing glucose, electrolytes, amino acids, multiple vitamins, and trace elements
	HINE Jelly, and HINE Jelly AQUA—a concentrated liquid diet, approved as comprehensive nutritional food for patients [zinc adjustment] categorized as food for special dietary use by the Consumer Affairs Agency
	Rebamipide tablets 100mg Otsuka launched - an anti-gastritis and anti-gastric ulcer agent
	HINEX REHADAYS launched—a beverage to support exercise and rehabilitation
2019	ENORAS Liquid for Enteral Use (for feeding tube and oral administration) launched
	Cellstor-S cell suspension and preservation solution and Cellstor-W cell wash and preservation solution launched
	HINE E-Gel LC launched—a concentrated liquid diet product
2020	Oral care gel (medicated toothpaste) HINORA (quasi-drug) and oral moisture gel HINORA Moisture Gel (oral cosmetic) launched
	Oral rehydration solution OS-1 series approved for new labeling including “prevention of deterioration of or recovery from dehydration” and “heatstroke with dehydration” as individually evaluated food for persons with medical conditions, categorized as food for special dietary use by the Consumer Affairs Agency
	VISCOCLEAR launched―gel to secure the visual field that is used for the endoscope for natural opening
	ENEFLUID Injection launched―an amino acid, carbohydrate, electrolyte, fat, and water-soluble vitamin injection
2021	HINEX E-Gel and HINEX E-gel LC launched― concentrated liquid diet products, as new products with changed names and some compositions
	Otsuka Gypto Pharmaceutical Egypt S.A.E. established in Egypt
2022	Actreen launched—an intermittent urological catheter
	Tolvaptan OD tablets 7.5/15 mg Otsuka launched―a vasopressin V2-receptor antagonist
	Lilium IP200 launched—an ultrasound bladder imaging device
	Pokenyu (Pocket Nutrition) service begun—a cloud service that helps professionals involved in home medical care identify and solve dietary and nutritional issues for home medical care patients
	OS-1 Apple Flavor added to the Oral Rehydration Solution OS-1 series
	OT-Balloon Catheter launched—an intermittent urological catheter
2023	Lilium one launched— a medical device that measures urine volume in the bladder specialized for single measurement