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History

We are a leading company of IV solutions in Japan. Our history is the very history of the development of Japanese IV products. We are committed to being the best partner of patients and healthcare professionals in the field of clinical nutrition.

Note: All products in this table below are sold by Otsuka Pharmaceutical Factory and other Otsuka Group companies. Generally, product names are those currently used. Product photos are generally those at the time of launch.

1921	Busaburo Otsuka founds Otsuka Seiyaku Kogyo-bu (Otsuka Pharmaceutical)
1921	Production of magnesium carbonate (listed in the Japanese Pharmacopoeia) from the bittern called “Nigari” begun
1936	Production of potassium bromide (listed in the Japanese Pharmacopoeia) begun and a series of new IV solution products decided to start
1940	Otsuka Pharmaceutical renamed Otsuka Pharmaceutical Factory
1946	Licenses obtained to manufacture the following injection solutions: calcium chloride injection, Ringer’s solution, etc.
1946	Production of pharmaceutical products including various intravenous solutions begun
1947	Masahito Otsuka succeeds Busaburo Otsuka as company owner
1948	License obtained to manufacture the glucose injection
1950	MEYLON Injection launched—a 7% sodium bicarbonate IV injection
1951	Glass vial for IV solutions launched
1952	Hydrazide Otsuka launched - an antitubercular drug
1953	Oronine Ointment launched - Otsuka Group's first over-the-counter product
1958	Saralin Tablets launched - a laxative product
1960	Amino acid supplements for nutritional deficiencies launched: PAN-AMIN, an essential amino acid injection, and PAN-AMIN S, a hypertonic injection of essential amino acids
1963	KN solution series (electrolyte solution) launched
1964	LOW MOLECULAR DEXTRAN D INJECTION launched—a circulatory improvement and extracorporeal perfusion solution
1967	Lactec Injection launched - an electrolyte solution (lactated Ringer's solution)
1968	Production of Japan's first plastic bottle for IV solutions begun
1969	Otsuka Pharmaceutical Factory becomes Otsuka Pharmaceutical Factory, Inc.
1969	Masahito Otsuka appointed President
1972	Oronine H Ointment launched - a product for treating minor skin conditions and injuries, containing chlorhexidine gluconate, which has excellent antiseptic properties
1973	P.T. Widatra Bhakti established in Indonesia
1974	MARTOS Injection 10% launched—a disaccharide IV injection
1974	Japan’s first injection solution in plastic ampule launched